QTL Map Information |
Chromosome: | 6 |
QTL Peak Location: | n/a |
QTL Span: | n/a 8.4-8.4 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs108993037 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Comparison-wise |
Threshold significance level: | Significant |
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P_values | 6.89E-6 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
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QTL Experiment in Brief |
Animals: | Animals were Holstein cows in Canada. |
Breeds associated:
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Design: | Animals were genotyped using the Bovine Geneseek Genomic Profiler 26K Beadchip, with data imputed to HD, and analyzed for serum IGF-1 level. A total of 636,471 SNPs were used for analysis. |
Analysis: | A mixed linear model based on the leave-one-chromosome out method was used for whole-genome association analysis. |
Software: | PLINK, SAS |
Notes: | |
Links: | Edit |
Reference |
Authors: | Gobikrushanth M, Purfield D C, Colazo M G, Wang Z, Butler S T, Ambrose D J |
Affiliation: | Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada, T6G 2P5; Teagasc, Animal & Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, Ireland, P61 C996 |
Title: | The relationship between serum insulin-like growth factor-1 (IGF-1) concentration and reproductive performance, and genome-wide associations for serum IGF-1 in Holstein cows |
Journal: | Journal of dairy science, 2018, 101(10): 9154-9167 |
Links: |
PubMed | Abstract | List all data
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