Release 56
(Apr 24, 2025)

QTL 167042 Description:

 Trait Information
Trait name: Insulin-like growth factor 1 level Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: IGFI Clinical Measurement Ontology: Serum insulin-like growth factor 1 level
 QTL Map Information
Chromosome:6
QTL Peak Location:n/a
QTL Span:n/a
8.4-8.4 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs108993037
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values6.89E-6
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein cows in Canada.
     Breeds associated:
    Design:Animals were genotyped using the Bovine Geneseek Genomic Profiler 26K Beadchip, with data imputed to HD, and analyzed for serum IGF-1 level. A total of 636,471 SNPs were used for analysis.
    Analysis:A mixed linear model based on the leave-one-chromosome out method was used for whole-genome association analysis.
    Software:PLINK, SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Gobikrushanth M, Purfield D C, Colazo M G, Wang Z, Butler S T, Ambrose D J
    Affiliation:Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada, T6G 2P5; Teagasc, Animal & Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, Ireland, P61 C996
    Title:The relationship between serum insulin-like growth factor-1 (IGF-1) concentration and reproductive performance, and genome-wide associations for serum IGF-1 in Holstein cows
    Journal:Journal of dairy science, 2018, 101(10): 9154-9167
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #30031580
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  • Cite this Data:

    Animal QTLdb: QTL167042 was published in 2018, and was curated into QTLdb on 2019-01-22. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:167042

     

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