Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

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Version: Enrich S: beta v0.8
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Data:

Number of disease & injury traits:24
Number of QTL / associations found:1,283
Number of chromosomes where QTL / associations are found:32

Chi-squared (χ2) test: are disease & injury traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X542.10960311.149928e-943.345245e-94
Chromosome 112224.66616319e-411.600000e-40
Chromosome 2401.73864314.606112e-661.133812e-65
Chromosome 316278.29064319e-411.600000e-40
Chromosome 437.41768310.19816962.348677e-01
Chromosome 549.50168310.018786002.404608e-02
Chromosome 6118.90152313.160753e-124.214337e-12
Chromosome 714.40912310.9951499.983293e-01
Chromosome 8195.97104317.262963e-261.056431e-25
Chromosome 9218.23128314.982455e-307.971928e-30
Chromosome 102.62416310.9983293258231159.983293e-01
Chromosome 1122.22808310.87571859.983293e-01
Chromosome 12616.56024315.02771e-1102.298382e-109
Chromosome 130.71616310.9983293258231159.983293e-01
Chromosome 1439.21336310.14775721.818550e-01
Chromosome 153822.04728319e-411.600000e-40
Chromosome 166094.95768319e-411.600000e-40
Chromosome 17266.34360313.111648e-395.240670e-39
Chromosome 1820.88144310.91500339.983293e-01
Chromosome 19578.73648313.291666e-1021.170370e-101
Chromosome 20118.90152313.160753e-124.214337e-12
Chromosome 21472.44792312.113410e-805.635760e-80
Chromosome 22578.73648313.291666e-1021.170370e-101
Chromosome 23347.49096313.426168e-557.831241e-55
Chromosome 24655.58136314.104092e-1184.377698e-117
Chromosome 25655.58136314.104092e-1184.377698e-117
Chromosome 26195.97104317.262963e-261.056431e-25
Chromosome 27542.10960311.149928e-943.345245e-94
Chromosome 28655.58136314.104092e-1184.377698e-117
Chromosome 29616.56024315.02771e-1102.298382e-109
Chromosome 30616.56024315.02771e-1102.298382e-109
Chromosome 31616.56024315.02771e-1102.298382e-109

Chi-squared (χ2) test: Which of the 24 disease & injury traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Bone fracture 354.47196 23 3.872768e-61 1.549107e-60
Degenerative suspensory ligament desmitis 96.12375 23 6.522354e-11 8.696472e-11
Dwarfism 40.94975 23 0.01199995 1.252169e-02
Equine arteritis virus 697.97056 23 1.187942e-132 2.851061e-131
Equine herpesvirus type 1-induced myeloencephalopathy 48.34616 23 0.001510571 1.647896e-03
Equine metabolic syndrome 75.62275 23 1.599446e-07 1.919335e-07
Equine neuroaxonal dystrophy/degenerative myeloencephalopathy 352.76631 23 8.640403e-61 2.962424e-60
Equine sarcoids 101.27313 23 8.480679e-12 1.197272e-11
Foal Immunodeficiency Syndrome 171.95456 23 8.950255e-25 1.652355e-24
Guttural pouch tympany 683.70867 23 1.196359e-129 1.435631e-128
Hydrocephalus 556.40061 23 6.109662e-103 4.887730e-102
Insect bite hypersensitivity 169.27079 23 2.909425e-24 4.987586e-24
Laminitis 39.09376 23 0.01937564 1.937564e-02
Melanoma 546.85715 23 6.022189e-101 3.613313e-100
Osteochondrosis 139.21363 23 1.294856e-18 2.071770e-18
Osteochondrosis dissecans 274.16948 23 7.278496e-45 2.183549e-44
Overriding spinous processes 364.57142 23 3.328983e-63 1.597912e-62
Recurrent airway obstruction 177.11233 23 9.223638e-26 1.844728e-25
Recurrent exertional rhabdomyolysis 206.75909 23 1.678302e-31 4.027925e-31
Recurrent laryngeal neuropathy 76.66235 23 1.092497e-07 1.379996e-07
Recurrent uveitis 120.52755 23 3.343712e-15 5.015568e-15
Rhodococcus equi infection 181.55915 23 1.291149e-26 2.817052e-26
Vitiligo 54.06708 23 0.0002621166 2.995618e-04
chronic progressive lymphedema 214.99507 23 4.09955e-33 1.093213e-32

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:32 χ2=47617.628160
Number of traits:24 df=713
Number of QTLs:1,283 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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