Release 56
(Apr 24, 2025)

QTL 19668 Description:

 Trait Information
Trait name: Systemic sclerosis incidence Vertebrate Trait Ontology: n/a
Reported name: Systemic sclerosis incidence Product Trait Ontology: n/a
Symbol: SSCL Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:2
QTL Peak Location:0.00 (cM)
QTL Span:n/a
58.8-58.8 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs14188947
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
LOD_score2.63
P_values0.020
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Birds were from a cross between UCD-200 (model for systemic sclerosis) and red jungle fowl chickens.
     Breeds associated:
    Design:Birds were genotyped for 326 SNPs and analyzed for incidence of avian systemic sclerosis.
    Analysis:Logistic regression and variance component methods were used.
    Software:R software
    Notes: 
    Links:Edit

     Reference
    Authors:Ek W, Sahlqvist AS, Crooks L, Sgonc R, Dietrich H, Wick G, Ekwall O, Andersson L, Carlborg Ö, Kämpe O, Kerje S
    Affiliation:Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Title:Mapping QTL affecting a systemic sclerosis-like disorder in a cross between UCD-200 and red jungle fowl chickens.
    Journal:Developmental and comparative immunology, 2012, 38(2):352-9
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Late SSc
    User inputs on reference #22796227
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  • Cite this Data:

    Animal QTLdb: QTL19668 was published in 2012, and was curated into QTLdb on 2013-02-19. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:19668

     

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