Wool quality traits like fiber diameter and its coefficient of variation, staple length and staple strength are important goals in Merino breeding programs. Although all these traits show polygenic variation, there are also single genes with major effect on these characters. Previous studies found evidence of linkage between keratin genes and fiber diameter and its coefficient of variation, staple strength and staple length review by Purvis and Franklin (2004). The objective of this work was to identify putative QTL affecting sheep wool production and quality in fine and superfine Merino sheep by analysis of specific regions of chromosomes 3, 4, 11 and 25.