Release 56
(Apr 24, 2025)

QTL 17710 Description:

 Trait Information
Trait name: Spinal curvature Vertebrate Trait Ontology: Vertebral column morphology trait
Reported name: Spinal curvature Product Trait Ontology: n/a
Symbol: SPINEC Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:12
QTL Peak Location:18.76 (cM)
QTL Span:18.76-18.76 (cM)
8.6-8.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs81219818
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values0.0295
Dominance effect:n/a
Additive effect:n/a
Associated Gene:SOX9 (SRY (sex determining region Y)-box 9)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from an F2 population of Duroc x Landrace pigs or a resource population of Yorkshire/Landrace/Duroc pigs.
     Breeds associated:
    Design:Animals were genotyped for 170 SNPs and 28 microsatellites and analyzed for back curvature.
    Analysis:Whole-genome association analysis was performed to identify areas associated with kyphosis. Positional candidate genes were selected and further association analysis was carried out using SNPs in 16 genes.
    Software:GenoProb, MTDFREML, Mendel 8.0.1
    Notes: 
    Links:Edit

     Reference
    Authors:Lindholm-Perry AK, Rohrer GA, Kuehn LA, Keele JW, Holl JW, Shackelford SD, Wheeler TL, Nonneman DJ
    Affiliation:USDA, ARS, U,S, Meat Animal Research Center, Clay Center, NE 68933-0166, USA
    Title:Genomic regions associated with kyphosis in swine
    Journal:BMC genetics, 2010, 11:112
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #21176156
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  • Cite this Data:

    Animal QTLdb: QTL17710 was published in 2010, and was curated into QTLdb on 2012-08-07. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:17710

     

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