Release 56
(Apr 24, 2025)

QTL 222840 Description:

 Trait Information
Trait name: Antibody response to Brucella suis Vertebrate Trait Ontology: Immune response trait
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: ABR-BS Clinical Measurement Ontology: Change in antibody titer
 QTL Map Information
Chromosome:8
QTL Peak Location:n/a
QTL Span:n/a
121.8-121.8 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs81404101
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:n/a
Test base:Comparison-wise
Threshold significance level:Significant
P_values3.59E-5
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were feral swine.
     Breeds associated:
    n/a
    Design:A case-control GWAS was performed to identify loci associated with differential antibody responses after natural infection with B. suis. Animals were genotyped using the GeneSeek Genomic Profiler for Porcine bead array. A total of 53,162 SNPs were used for analysis.
    Analysis:Single-locus GWAS were performed using efficient mixed-model association eXpedited (EMMAX) methodology.
    Software:SVS, PLINK 1.9
    Notes: 
    Links:Edit

     Reference
    Authors:Pierce CF, Brown VR, Olsen SC, Boggiatto P, Pedersen K, Miller RS, Speidel SE, Smyser TJ
    Affiliation:United States Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services, National Wildlife Research Center, Fort Collins, CO, United States
    Title:Loci Associated With Antibody Response in Feral Swine (Sus scrofa) Infected With Brucella suis
    Journal:Frontiers in veterinary science, 2020, 7: 554674
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:dominant model
    User inputs on reference #33324693
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  • Cite this Data:

    Animal QTLdb: QTL222840 was published in 2020, and was curated into QTLdb on 2021-06-08. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:222840

     

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