Release 56
(Apr 24, 2025)

QTL 258008 Description:

 Trait Information
Trait name: Subcutaneous fat thickness Vertebrate Trait Ontology: Subcutaneous adipose thickness
Trait details: backfat Product Trait Ontology: n/a
Symbol: BFT Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:5
QTL Peak Location:n/a
QTL Span:n/a
Upper, "Suggestive":n/a
Upper, "Significant":rs340089436
Peak:
Lower, "Significant":rs321338191
Lower, "Suggestive":n/a
Marker type:Haplotype
Analysis type:QTL
Model tested:n/a
Test base:-
Threshold significance level:Significant
P_values0.00000000000000
Dominance effect:n/a
Additive effect:n/a
Associated Gene:CCND2 (cyclin D2)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from five pig populations: Synthetic (Large White-based), Pietrain, Landrace, Large White, and Duroc.
     Breeds associated:
    Design:Animals were genotyped using varying SNP chips, with medium-density genotypes imputed to HD, and association analysis was performed for backfat thickness.
    Analysis:A linear animal model was used for single-SNP GWAS. Subsequently, a haplotype-based association analysis was performed using the same mixed model. Further, eQTL analysis was performed for the identified lead SNP.
    Software:GCTA, ASReml v3.0, Beagle v5.1, SAMtools v1.9
    Notes: 
    Links:Edit

     Reference
    Authors:Oliveira HC, Derks MFL, Lopes MS, Madsen O, Harlizius B, van Son M, Grindflek EH, Gòdia M, Gjuvsland AB, Otto PI, Groenen MAM, Guimaraes SEF
    Affiliation:Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil
    Title:Fine Mapping of a Major Backfat QTL Reveals a Causal Regulatory Variant Affecting the CCND2 Gene
    Journal:Frontiers in Genetics, 2022, 13: 871516
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Synthetic population
    User inputs on reference #35692822
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  • Cite this Data:

    Animal QTLdb: QTL258008 was published in 2022, and was curated into QTLdb on 2022-06-28. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:258008

     

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