QTL Map Information |
Chromosome: | 5 |
QTL Peak Location: | n/a |
QTL Span: | n/a
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Upper, "Suggestive": | n/a |
Upper, "Significant": | rs340089436 |
Peak: | |
Lower, "Significant": | rs321338191 |
Lower, "Suggestive": | n/a |
Marker type: | Haplotype |
Analysis type: | QTL |
Model tested: | n/a |
Test base: | - |
Threshold significance level: | Significant |
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P_values | 0.00000000000000 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | CCND2 (cyclin D2) |
Cis/Trans acting type: |  |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Animals were from five pig populations: Synthetic (Large White-based), Pietrain, Landrace, Large White, and Duroc. |
Breeds associated:
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Design: | Animals were genotyped using varying SNP chips, with medium-density genotypes imputed to HD, and association analysis was performed for backfat thickness. |
Analysis: | A linear animal model was used for single-SNP GWAS. Subsequently, a haplotype-based association analysis was performed using the same mixed model. Further, eQTL analysis was performed for the identified lead SNP. |
Software: | GCTA, ASReml v3.0, Beagle v5.1, SAMtools v1.9 |
Notes: | |
Links: | Edit |
Reference |
Authors: | Oliveira HC, Derks MFL, Lopes MS, Madsen O, Harlizius B, van Son M, Grindflek EH, Gòdia M, Gjuvsland AB, Otto PI, Groenen MAM, Guimaraes SEF |
Affiliation: | Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil |
Title: | Fine Mapping of a Major Backfat QTL Reveals a Causal Regulatory Variant Affecting the CCND2 Gene |
Journal: | Frontiers in Genetics, 2022, 13: 871516 |
Links: |
PubMed | Abstract | List all data
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Additional Information |
Comments: | Synthetic population |

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